CODEBOOK V2018: Prospective Cohort Study of Kidney Disease in Children 7-28-2020 L21 - Specimen Collection Form for Visit 2 Start ____Field____ Section/ Column Len Format Variable Question Description Code ------ --- --------- ---------------- ------------ ------------------------------ ------------------------------ 1 6 6.0 CASEID A.1 Participant ID 100000= 100000 . . 699999= 699999 7 3 3.0 VISIT A.2 Visit # 000= 000 . . 990= 990 10 8 $ VERSSC A.3 Form version 09/01/04= 09/01/04 . . 12/31/18= 12/31/18 18 7 7.3 SCVISDAT A.4 Specimen collection date in 0.000= 0.000 years duration of year from the . baseline visit . 50.000= 50.000 years -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 25 3 $ SCINITL A.5 Initials of person completing Character form 28 2 2.0 ACCELVIS OldA.6 Old: Accelerated visit 1= Yes 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 30 2 2.0 SCFEMCBP B.1 Participant is female of 1= YES child-bearing potential 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 32 7 7.3 SCUPRGDT B.2 Date of urine pregnancy test 0.000= 0.000 years in duration of year from the . baseline visit . 50.000= 50.000 years -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 39 2 2.0 SCUPRGRS B.2.b Urine pregnancy test result 1= Positive 2= Negative -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 41 2 2.0 SCMUPGFR OldB.3 Old: Make-up GFR visit 1= Yes 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 43 7 7.3 SCMUGFRD OldB.3.a Old: Make-up GFR date in 0.000= 0.000 years duration of year from the . baseline visit . 50.000= 50.000 years -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 50 2 2.0 SCMUIVIN OldB.4.a Old: Reason for make-up GFR - 1= YES IV infiltration 2= NO -1= N.A. (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 52 2 2.0 SCMU4BLD OldB.4.b Old: Reason for make-up GFR - 1= YES unable to draw 4 blood samples 2= NO -1= N.A. (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 54 2 2.0 SCMUOTHR OldB.4.c Old: Reason for make-up GFR - 1= YES other reason 2= NO -1= N.A. (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 56 50 $ SCMUOTSP OldB.4.c.i Old: Reason for make-up GFR - Character specify other reason 106 2 2.0 SCFURINE B.3.a Urine creatinine/protein/ 1= YES albumin sample obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 108 2 2.0 SCFURESN B.3.b Reason urine creatinine/ 1= Not required protein/albumin sample not 2= Difficult urine collection obtained 3= Participant refused 4= Collection contamination 5= Inadvertently destroyed 6= Oversight 7= Insuffiecient Volume -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 110 2 2.0 SCFMURIN B.3.c.i Urine creatinine/protein/ 1= YES albumin is 1st morning urine 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 112 5 time5. SCURTIME B.3.c.ii Time urine creatinine/protein/ 01:00= 01:00 albumin collected . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 117 2 2.0 SCURMER B.3.c.ii AM/PM for time urine 1= AM creatinine/protein/albumin 2= PM collected -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 119 2 2.0 SCURMTAL OldB.4.a Old: Urine heavy metals 1= YES sample obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 121 2 2.0 SCUMRESN OldB.4.b Old: Reason urine heavy 1= Not required metals sample not obtained 2= Difficult urine collection 3= Participant refused 4= Collection contamination 5= Inadvertently destroyed 6= Oversight 7= Insuffiecient Volume -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 123 2 2.0 SCUMSMVD B.4.c.i Old: Same void used to 1= YES collect CBL and heavy metal 2= NO samples -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 125 2 2.0 SCFUHOME OldB.5.c.i Old: Urine collected at home 1= YES 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 127 5 time5. SCTIMZRO C.1 Time of time zero blood draw 01:00= 01:00 . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 132 2 2.0 SCMERZRO C.1 AM/PM for time of time=zero 1= AM blood draw 2= PM -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 134 2 2.0 SCRNCHEM C.2.a Renal/uric acid chemistries 1= YES sample obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 136 2 2.0 SCRCRESN C.2.b Reason renal/uric acid 1= Not required chemistries sample not 2= Difficult blood draw obtained 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 138 2 2.0 SCRCAPPR C.2.c Renal/uric acid chemistries - 1= Grossly (Dark Red) appearance of serum after 2= Moderately (Red/Light Red) centrifuging 3= Slightly (Pink) 4= Not Hemolyzed (Yellow) -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 140 2 2.0 SCCYSTAC C.3.a Cystatin C sample obtained 1= YES 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 142 2 2.0 SCCCRESN C.4.b Reason Cystatin C sample not 1= Not required obtained 2= Difficult blood draw 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 144 7 7.3 SCCCFROZ C.3.c Date Cystatin C frozen in 0.000= 0.000 years duration of year from the . baseline visit . 50.000= 50.000 years -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 151 2 2.0 SCLOCCBC C.4a.a Local CBC sample obtained 1= YES 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 153 2 2.0 SCLCRESN C.4a.b Reason Local CBC sample not 1= Not required obtained 2= Difficult blood draw 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 155 2 2.0 SCLOCRPL C.4b.a Local Renal Panel sample 1= YES obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 157 2 2.0 SCLRRESN C.4b.b Reason Local Renal Panel 1= Not required sample not obtained 2= Difficult blood draw 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 159 2 2.0 SCFASTLP C.5.a Serum for lipid panel sample 1= YES obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 161 2 2.0 SCLPRESN C.5.b Reason lipid panel sample not 1= Not required obtained 2= Difficult blood draw 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 163 2 2.0 SCLPFAST C.5.c Child fasted after midnight 1= YES 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 165 2 2.0 SCWBMTAL OldC.6.a Old: Whole blood for Heavy 1= YES Metals sample obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 167 2 2.0 SCWMRESN OldC.6.b Old: Reason whole blood for 1= Not required Heavy Metals sample not 2= Difficult blood draw obtained 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 169 20 $ SCFAXNUM OldC.6.a Old: Fax number for results Character 189 30 $ SCRCNAME OldC.6.b Old: Recipient's name Character 219 2 2.0 SCCONMCK C.6 Participant consented to have 1= Yes biological samples stored at 2= No NIDDK -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 221 2 2.0 SCSRMCKS C.7.a Serum for NIDDK Biosample 1= YES Repository sample obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 223 2 2.0 SCSRRESN C.7.b Reason serum for NIDDK 1= Not required Biosample Repository sample 2= Difficult blood draw not obtained 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 225 7 7.3 SCSRFROZ C.7.c Date serum for NIDDK 0.000= 0.000 years Biosample Repository frozen . in duration of year from the . baseline visit 50.000= 50.000 years -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 232 2 2.0 SCPLMCKS C.8.a Plasma for NIDDK Biosample 1= YES Repository sample obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 234 2 2.0 SCPLRESN C.8.b Reason plasma for NIDDK 1= Not required Biosample Repository sample 2= Difficult blood draw not obtained 3= Participant refused 4= Red blood cell contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 236 7 7.3 SCPLFROZ C.8.c Date plasma for NIDDK 0.000= 0.000 years Biosample Repository frozen . in duration of year from the . baseline visit 50.000= 50.000 years -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 243 2 2.0 SCURMCKS D.1.a Urine for NIDDK Biosample 1= YES Repository sample obtained 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 245 2 2.0 SCURRESN D.1.b Reason urine for NIDDK 1= Not required Biosample Repository sample 2= Difficult urine collection not obtained 3= Participant refused 4= Collection contamination 5= Inadvertently destroyed 6= Oversight -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 247 2 2.0 SCURCRYO D.1.c.i Supernate decanted into urine 1= YES transport cyrovials 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 249 7 7.3 SCURFROZ OldD.1.c.ii Old: Date urine for NIDDK 0.000= 0.000 years Biosample Repository frozen . in duration of year from the . baseline visit 50.000= 50.000 years -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 256 2 2.0 SCMPLLAB OldE.1 Old: Basic metabolic panel 1= YES performed at local lab 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 258 2 2.0 SCFULLAB E.2 Urine protein to creatinine 1= YES assay performed at local 2= NO laboratory -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 260 2 2.0 SCPCIOHX E.3 Participant is completing 1= YES iohexol study visit 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 262 5 5.2 SCISWTWM F.1.a Infusion syringe weight - 5.00= 5.00 with iohexol . . 25.00= 25.00 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 267 5 5.2 SCISWTAI F.1.b Infusion syringe weight - 4.00= 4.00 after infusion . . 15.00= 15.00 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 272 5 time5. SCIOSTIM G.1.a Iohexol infusion start time 01:00= 01:00 . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 277 2 2.0 SCIOSMER G.1.a AM/PM for iohexol infusion 1= AM start time 2= PM -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 279 2 2.0 SC10MBL OldG.2.a.i Old: Minutes on timer - B1 10 5= 5 minute . . 15= 15 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 281 5 time5. SC10MTIM OldG.2.a.ii Old: Time of B1 10 minute 01:00= 01:00 blood draw . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 286 2 2.0 SC10MMER OldG.2.a.ii Old: AM/PM for time of B1 10 1= AM minute blood draw 2= PM -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 288 2 2.0 SC10DIF OldG.2.a.iii Old: Difficult blood draw - 1= YES B1 10 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 290 4 4.1 SC10MBV OldG.2.a.iv Old: Blood volume collected - 0.1= 0.1 B1 10 minute . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 294 2 2.0 SC10MCS OldG.2.a.v Old: Centrifuged at clinical 1= YES site - B1 10 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 296 2 2.0 SC10M2A OldG.2.b.i Old: Minutes on timer - B1 10 10= 10 2nd attempt . . 20= 20 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 298 5 time5. SC10M2TM OldG.2.b.ii Old: Time of B1 10 minute 01:00= 01:00 blood draw - 2nd attempt . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 303 2 2.0 SC10M2MR OldG.2.b.ii Old: AM/PM for time of B1 10 1= AM minute blood draw - 2nd 2= PM attempt -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 305 2 2.0 SC10DIF2 OldG.2.b.iii Old: Difficult blood draw - 1= YES B1 10 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 307 4 4.1 SC10M2BV OldG.2.b.iv Old: Blood volume collected - 0.1= 0.1 B1 10 2nd attempt . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 311 2 2.0 SC10M2CS OldG.2.b.v Old: Centrifuged at clinical 1= YES site - B1 10 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 313 3 3.0 SCPSTSYS G.2.a.i Post-infusion blood pressure - 20= 20 systolic . . 240= 240 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 316 3 3.0 SCPSTDIA G.2.a.i Post-infusion blood pressure - 20= 20 diastolic . . 200= 200 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 319 5 5.1 SCPSTTMP G.2.b.i Post-infusion temperature 34.0= 34.0 . . 105.0= 105.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 324 2 2.0 SCCNTFAR G.2.b.i Centigrade or Farenheit 1= Centigrade Typical range: 36.1-38.3 2= Farenheit Typical range: 94.5-100.6 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 326 3 3.0 SCPSTPLS G.2.c.i Post-infusion pulse 20= 20 measurement . . 180= 180 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 329 2 2.0 SCPSTRES G.2.d.i Post-infusion respirations 4= 4 . . 44= 44 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 331 2 2.0 SC30MBL OldG.4.a.i Old: Minutes on timer - B2 30 25= 25 minute . . 99= 99 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 333 5 time5. SC30MTIM OldG.4.a.ii Old: Time of B2 30 minute 01:00= 01:00 blood draw . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 338 2 2.0 SC30MMER OldG.4.a.ii Old: AM/PM for time of B2 30 1= AM minute blood draw 2= PM -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 340 2 2.0 SC30DIF OldG.4.a.iii Old: Difficult blood draw - 1= YES B2 30 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 342 4 4.1 SC30MBV OldG.4.a.iv Old: Blood volume collected - 0.1= 0.1 B2 30 minute . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 346 2 2.0 SC30MCS OldG.4.a.v Old: Centrifuged at clinical 1= YES site - B2 30 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 348 2 2.0 SC30M2A OldG.4.b.i Old: Minutes on timer - B2 30 25= 25 2nd attempt . . 99= 99 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 350 5 time5. SC30M2TM OldG.4.b.ii Old: Time of B2 30 minute 01:00= 01:00 blood draw - 2nd attempt . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 355 2 2.0 SC30M2MR OldG.4.b.ii Old: AM/PM for time of B2 30 1= AM minute blood draw - 2nd 2= PM attempt -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 357 2 2.0 SC30DIF2 OldG.4.b.iii Old: Difficult blood draw - 1= YES B2 30 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 359 4 4.1 SC30M2BV OldG.4.b.iv Old: Blood volume collected - 0.1= 0.1 B2 30 2nd attempt . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 363 2 2.0 SC30M2CS OldG.4.b.v Old: Centrifuged at clinical 1= YES site - B2 30 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 365 2 2.0 SC120HBL G.3.a.i Hours on timer - B1 120 hour 1= 1 . . 3= 3 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 367 2 2.0 SC120MBL G.3.a.i Minutes on timer - B1 120 0= 0 minute . . 59= 59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 369 5 time5. SC120MTM G.3.a.ii Time of B1 120 minute blood 01:00= 01:00 draw . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 374 2 2.0 SC120MMR G.3.a.ii AM/PM for time of B1 120 1= AM minute blood draw 2= PM -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 376 2 2.0 SC120DIF G.3.a.iii Difficult blood draw - B1 120 1= YES minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 378 2 2.0 SC120VEN G.3.a.iv Drawn by venipuncture - B1 1= YES 120 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 380 4 4.1 SC120MBV G.3.a.v Blood volume collected - B1 0.1= 0.1 120 minute . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 384 2 2.0 SC120MCS G.3.a.vi Centrifuged at clinical site - 1= YES B1 120 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 386 2 2.0 SC120H2A G.3.b.i Minutes on timer - B1 120 1= 1 hour 2nd attempt . . 3= 3 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 388 2 2.0 SC120M2A G.3.b.i Minutes on timer - B1 120 2nd 0= 0 attempt mins . . 59= 59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 390 5 time5. SC120M2T G.3.b.ii Time of B1 120 minute blood 01:00= 01:00 draw - 2nd attempt . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 395 2 2.0 SC120M2M G.3.b.ii AM/PM for time of B1 120 1= AM minute blood draw - 2nd 2= PM attempt -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 397 2 2.0 SC120DF2 G.3.b.iii Difficult blood draw - B1 120 1= YES 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 399 2 2.0 SC120VN2 G.3.b.iv Drawn by venipuncture - B1 1= YES 120 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 401 4 4.1 SC1202BV G.3.b.v Blood volume collected - B1 0.1= 0.1 120 2nd attempt . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 405 2 2.0 SC1202CS G.3.b.vi Centrifuged at clinical site - 1= YES B1 120 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 407 2 2.0 SC300HBL G.4.a.i Hours on timer - B2 300 hour 4= 4 . . 6= 6 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 409 2 2.0 SC300MBL G.4.a.i Minutes on timer - B2 300 0= 0 minute . . 59= 59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 411 5 time5. SC300MTM G.4.a.ii Time of B2 300 minute blood 01:00= 01:00 draw . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 416 2 2.0 SC300MMR G.4.a.ii AM/PM for time of B2 300 1= AM minute blood draw 2= PM -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 418 2 2.0 SC300DIF G.4.a.iii Difficult blood draw - B2 300 1= YES minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 420 2 2.0 SC300VEN G.4.a.iv Drawn by venipuncture - B2 1= YES 300 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 422 4 4.1 SC300MBV G.4.a.v Blood volume collected - B2 0.1= 0.1 300 minute . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 426 2 2.0 SC300MCS G.4.a.vi Centrifuged at clinical site - 1= YES B2 300 minute 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 428 2 2.0 SC300H2A G.4.b.i Minutes on timer - B2 300 4= 4 hour 2nd attempt . . 6= 6 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 430 2 2.0 SC300M2A G.4.b.i Minutes on timer - B2 300 2nd 0= 0 attempt mins . . 59= 59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 432 5 time5. SC300M2T G.4.b.ii Time of B2 300 minute blood 01:00= 01:00 draw - 2nd attempt . . 12:59= 12:59 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 437 2 2.0 SC300M2M G.4.b.ii AM/PM for time of B2 300 1= AM minute blood draw - 2nd 2= PM attempt -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 439 2 2.0 SC300DF2 G.4.b.iii Difficult blood draw - B2 300 1= YES 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 441 2 2.0 SC300VN2 G.4.b.iv Drawn by venipuncture - B2 1= YES 300 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 443 4 4.1 SC3002BV G.4.b.v Blood volume collected - B2 0.1= 0.1 300 2nd attempt . . 8.0= 8.0 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 447 2 2.0 SC3002CS G.4.b.vi Centrifuged at clinical site - 1= YES B2 300 2nd attempt 2= NO -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 449 2 2.0 SCNHCV1B H.2 Nail clippings and hair 1= Yes samples were collected at V1b 2= No or V2 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 451 2 2.0 SCPCNSNT H.3 Participant consented to have 1= Yes samples stored at NIDDK 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 453 2 2.0 SCACRYLC H.4 Participant has acrylic nails 1= Yes 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 455 2 2.0 SC10FNLS H.5 10 fingernail clippings 1= Yes collected 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 457 2 2.0 SCNMFNLS H.5.a Number of fingernails 0= 0 collected . . 9= 9 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 459 2 2.0 SC10FRSN H.5.b Reason 10 fingernail 1= Nails not long enough clippings not collected 2= Other -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 461 75 $ SCSPOTFN H.5.b.i Specify other reason 10 Character fingernails not collected 536 2 2.0 SC10TNLS H.6 10 toenail clippings collected 1= Yes 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 538 2 2.0 SCNMTNLS H.6.a Number of toenails collected 0= 0 . . 9= 9 -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 540 2 2.0 SC10TRSN H.6.b Reason 10 toenail clippings 1= Nailfungus or discoloration not collected 2= Nails not long enough 3= Other -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 542 75 $ SCSPOTTN H.6.b.i Specify other reason 10 Character toenails not collected 617 2 2.0 SCALTHR I.1 Participant has altered hair 1= Yes 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 619 2 2.0 SC20HAIR I.2 Able to cut 20 fibers of hair 1= Yes 2= No -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 621 2 2.0 SC20HRSN I.2.a Reason 20 hair fibers not 1= Hair not long enough collected 2= Other -1= NA (Skipped) -7= Refusal -8= Don't know -9 or Blank= Missing 623 75 $ SCSPOTHR I.2.b.i Specify other reason 20 hair Character fibers not collected 698 1 $ ESTAT Edit status A.0 D= Dirty C= Clean P= Pending 699 6 $ VERSION Version number of data P01= Version 01 . . P99= Version 99