Public Release Type:
Journal
Publication Year: 2015
Authors:
Lisker-Melman M,
Terrault N,
Khalili M,
Chung R,
Feld J,
Ghany M,
Hepatitis B Research Network (HBRN),
Kim WR,
Kowdley K,
Lok A,
Lombardero M,
Sanyal A,
Shuhart M
Studies:
Hepatitis B Research Network
Due to rise in obesity, metabolic syndrome (MS) is prevalent in western countries affecting about 25% of adults in United States. MS is associated with adverse liver disease outcomes including disease progression and hepatocellular carcinoma (HCC). However, the impact of MS on liver disease markers among patients with chronic hepatitis B infection (CHB) living in North America (NA) have not been well studied.We sought to determine the prevalence of MS and its influence on ALT levels at cohort entry and change in ALT over time in a large multi-ethnic NA cohort of patients infected with HBV.