PubMed ID:
25399733
Public Release Type:
Journal
Publication Year: 2014
Affiliation: From the University of Colorado, Denver (R.W.S., G.B.); University of Pittsburgh School of Medicine, Pittsburgh (K.Z.A., K.T.B., C.G.M.); Tufts Medical Center (R.D.P., D.C.M.) and Beth Israel Deaconess Medical Center (T.I.S., P.G.C.) - both in Boston; Mayo Clinic College of Medicine, Rochester, MN (V.E.T., M.C.H., P.C.H.); Cleveland Clinic, Cleveland (W.E.B.); Kansas University Medical Center, Kansas City (F.T.W., J.J.G.); Emory University School of Medicine, Atlanta (F.F.R.-O., A.B.C.); and the National Institutes of Health, Bethesda, MD (M.F.F.).
DOI:
https://doi.org/10.1056/NEJMoa1402685
Authors:
Greene T,
Perrone RD,
Perrone R,
Torres VE,
Abebe KZ,
Abebe KZ,
Bae K,
Bae KT,
Bost JE,
Braun W,
Braun WE,
Briggs J,
Brosnahan G,
Brosnahan G,
Chapman A,
Chapman AB,
Czarnecki P,
Czarnecki PG,
El-Zoghby Z,
Flessner M,
Flessner MF,
Gitomer B,
Glockner J,
Grantham J,
Grantham JJ,
Halin N,
HALT-PKD Trial Investigators,
Harris P,
Harris PC,
Henrich W,
Hogan MC,
Hogan MC,
Kelleher C,
King B Jr,
Leonard M,
Martin D,
Masoumi A,
McCullough P,
Meyers CM,
Miller JP,
Miskulin D,
Miskulin DC,
Mittal P,
Moe S,
Moore CG,
Moore CG,
Nurko S,
Patel N,
Pedrosa I,
Rahbari-Oskoui F,
Rahbari-Oskoui FF,
Remer E,
Rocco M,
Schrier R,
Schrier RW,
Shayman J,
Star R,
Steinman T,
Steinman TI,
Thompson PA,
Torres V,
Wang C,
Wei J,
Wendler D,
Wetzel L,
Winklhofer F,
Winklhofer FT,
Yu A
Hypertension is common in autosomal dominant polycystic kidney disease (ADPKD) and is associated with increased total kidney volume, activation of the renin-angiotensin-aldosterone system, and progression of kidney disease.