PubMed ID:
24846279
Public Release Type:
Journal
Publication Year: 2014
Affiliation: Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address: nchalasa@iu.edu.
DOI:
https://doi.org/10.1016/j.cgh.2014.05.010
Authors:
Vuppalanchi R,
Kleiner DE,
Chalasani N,
Brunt EM,
Comerford M,
Deppe R,
Jain AK,
Lavine JE,
Loomba R,
Masuoka HC,
Molleston JP,
Neuschwander-Tetri BA,
Schwimmer JB,
Tonascia J,
Yates K
Studies:
Nonalcoholic Steatohepatitis Clinical Research Network
Cross-sectional studies have associated serum levels of the keratin 18 (K18) fragment with histologic features of liver in individuals with nonalcoholic fatty liver disease (NAFLD). We investigated the relationship between changes in serum levels of K18 and changes in liver histology in adults and children with NAFLD.