Public Release Type:
Journal
Publication Year: 2012
Authors:
Kleiner DE,
Behling C,
Belt P,
Brunt EM,
Guy CD,
Murray KF,
Neuschwander-Tetri BA,
Torbenson M,
Yeh MM
Studies:
Nonalcoholic Steatohepatitis Clinical Research Network
Diffuse hepatic glycogenosis is the dominant histological finding in glycogenic hepatopathy, a condition sometimes seen with poorly controlled diabetes mellitus type 1 (DM1). A similar histologic feature (glassy, pale cytoplasmic accumulations on H&E stain) has been noted in pediatric NAFLD liver biopsies which lacked the typical clinicopathological pattern of glycogenic hepatopathy. Our aim was to further characterize the clinical and histological correlations of this finding.