Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial.

PubMed ID: 21714999
Public Release Type: Journal
Publication Year: 2011
Affiliation: Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
DOI: https://doi.org/10.1016/S0140-6736(11)60895-7
Authors: Cowie C, Cordova E, Davis R, Fernandez S, Arthur J, Wherrett D, Kovalakovska R, Eisel LA, Ahenkorah B, Sriskandarajah M, Ricci MJ, Herold KC, Feldman L, Sherwin R, Orchard T, Nerup J, Naji A, Laffel L, Braun J, Blumberg E, Spain L, Savage P, Leschek E, Fradkin J, Raiden E, Quinlan S, Phoebus D, Hess KO, McGee PF, McDonough S, Krause-Steinrauf H, Harding P, Foulkes M, Lachin JM, Shor A, Nallamshetty L, Kieffer M, Granger M, Freeman D, Bassi M, Young K, Xu P, Wootten M, Terry A, Sadler K, Roberts A, Pilger J, Paulus K, Parrimon Y, O'Donnell R, Muller S, Ritzie AL, Lloyd J, Liu S, Linton C, Law P, Henry M, Hays B, Guillette H, Ginem J, Ford J, Eberhard C, Cuthbertson D, Boulware D, Boonstra M, Beam C, Badias F, Alies P, Adams T, Abbondondolo M, Ramiro J, Bundy B, Krischer JP, Sosenko JM, Santiago I, Rafkin L, Kenyon NS, Greenbaum CJ, Skyler JS, Zafonte SJ, Ridge J, Peyman J, Malozowski S, Lachin JM, Krause-Steinrauf H, Foulkes M, Spain L, Savage P, Rafkin L, Leschek E, Krischer JP, Greenbaum CJ, Bourcier K, Skyler JS, Ziegler A, Rodriguez H, Ridge J, Peyman J, Pescovitz M, Parkman R, Orban T, Nepom G, Nanto-Salonen K, Lachin JM, Kaufman FR, Jordan S, Hering B, Cowie C, Brown D, Bluestone J, Benoist C, Spain L, Leschek E, Fradkin J, Winter W, Wilson DM, Wherrett D, Wagner J, Trucco M, Thomas J, Simell O, Siegelman M, Sherwin R, Schatz D, Savage P, Russell W, Roncarolo MG, Raskin P, Pugliese A, Peakman M, Palmer JP, Moran A, Marks J, Mahon J, Krischer JP, Insel R, Herold K, Harrison L, Greenbaum C, Grave G, Gottlieb P, Goland R, Gitelman S, Fathman CG, Eisenbarth GS, DiMeglio L, Colman P, Clare-Salzler M, Chase HP, Buckner J, Bosi E, Blum J, Bingley P, Becker D, Bourcier K, Anderson M, Skyler JS, Type 1 Diabetes TrialNet GAD Study Group, Skyler JS, Krischer JP, Wilson DM, Schatz D, Rodriguez H, Raskin P, Palmer JP, Orban T, Moran A, Monzavi R, Marks JB, Herold KC, Greenbaum CJ, Gottlieb PA, Goland R, Gitelman SE, DiMeglio LA, Becker DJ, Bundy B, Wherrett DK, Tsiatis A, Veatch R, Wallace D, Lernmark A, Lo B, Mitchell H, Steffes M, Zinman B, Loechelt B, Baden L, Green M, Weinberg A, Babu S, Eisenbarth GS, Marcovina S, Palmer JP, Weinberg A, Winter W, Yu L, Wherett D, Bingley P, Cook R, Mahon J, Palmer J, Greenbaum C, Krischer J, Leschek E, Loechelt B, Rafkin L, Skyler JS, Shor A, Spain L, Lachin JM, Krause-Steinrauf H, McGee PF, Greenbaum C, Bollyky J, Sanda S, Tridgell D, McCulloch-Olson M, Vendettuoli H, Hefty D, Ramey M, Webber C, Kuhns K, Hilderman N, Dove A, Hammond M, Klein J, Batts E, Monzavi R, Halvorson M, Bock M, Fisher L, Jeandron D, Wood J, Goland R, Greenberg E, Gallagher MP, Trast J, Chan M, Smith K, Rodriguez H, Pescovitz M, DiMeglio L, Lynch S, Nicholson M, Mendez M, Terrell J, Orban T, Wolfsdorf J, Ricker A, Jalahej H, Conboy D, Zhang H, Fay S, Wilson DM, Buckingham BA, Aye T, Esrey T, Soto A, Perry J, Baker B, Berry B, Gitelman SE, Rosenthal SM, Anderson M, Adi S, Breen K, Hamilton C, Gottlieb P, Michaels A, Chase HP, Ulmer S, Barry S, Meyers L, Lehr D, Tuthill L, Weiner L, Schatz D, Haller M, Clare-Salzler M, Cook R, Mancini D, Abraham A, Hicks E, Cole G, Marks JB, Pugliese A, Matheson D, Blaschke C, Arazo L, Cisneros M, Acosta B, Moran A, Nathan B, Wagner J, Albright-Fischer T, Smith J, Street A, Leschyshyn J, Kwong C, Becker D, Toledo F, Libman I, Riley K, Delallo K, Smith K, Gwynn D, Wohlers G, Gurtunca N, Raskin P, White P, Dickson B, Adhikari S, Siegelman M, Alford M, Torres N, Harden T, Pruneda L