PubMed ID:
21172393
Public Release Type:
Journal
Publication Year: 2011
Affiliation: Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: nchalasa@iupui.edu.
DOI:
https://doi.org/10.1016/j.jhep.2010.11.021
Authors:
Vuppalanchi R,
Chalasani N,
Brunt EM,
Cummings OW,
Tandra S,
Ünalp-Arida A,
Wilson LA,
Yeh MM
Studies:
Nonalcoholic Steatohepatitis Clinical Research Network
Liver biopsies from patients with nonalcoholic fatty liver disease (NAFLD) sometimes exhibit non-zonal aggregates of hepatocytes with microvesicular steatosis, but its prevalence and significance are unclear. In this study, we have evaluated the frequency of microvesicular steatosis and assessed its association with histological markers of disease severity in a large sample of NAFLD liver biopsies.