PubMed ID:
21156319
Public Release Type:
Journal
Publication Year: 2011
Affiliation: Department of Medicine, Medical University of South Carolina, Charleston, SC, United States. virellam@musc.edu
DOI:
https://doi.org/10.1016/j.atherosclerosis.2010.11.012
Authors:
Baker NL,
DCCT/EDIC Research Group,
Hunt KJ,
Lachin J,
Lopes-Virella MF,
Nathan D,
Virella G
Studies:
Diabetes Control and Complications Trial
Oxidized LDL (oxLDL) and oxLDL antibodies form immune complexes (IC) that reflect essential components in the development of atherosclerosis: dyslipidemia, oxidative stress and induction of a pro-inflammatory humoral immune response. We measured oxLDL in IC (oxLDL-IC) isolated from patients with type 1 diabetes to assess the relationship between oxLDL-IC and coronary artery calcification (CAC).