PubMed ID:
20728571
Public Release Type:
Journal
Publication Year: 2010
Affiliation: Duke University, Durham, North Carolina, USA. suzuk004@mc.duke.edu
DOI:
https://doi.org/10.1016/j.cgh.2010.08.005
Authors:
Suzuki A,
Abdelmalek MF,
Unalp-Arida A,
Yates K,
Sanyal A,
Guy C,
Diehl AM
Studies:
Nonalcoholic Steatohepatitis Clinical Research Network
In overnourished individuals, impaired peripheral fat storage (ie, reduced fat mass in extremities) can increase delivery of surplus calories to the organs other than peripheral adipose tissues, including the liver (ie, lipid overload), and facilitate disease progression in patients with nonalcoholic fatty liver disease (NAFLD). We investigated whether peripheral and/or abdominal adipose depot size correlates with stage of hepatic fibrosis in patients with NAFLD in sex- and/or menopausal stage-specific manners.