PubMed ID:
19143814
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Twin Research Unit, King's College London, St Thomas' Hospital, London, UK. ana.valdes@kcl.ac.uk
DOI:
https://doi.org/10.1111/j.1463-1326.2008.01002.x
Authors:
Thomson G,
Type 1 Diabetes Genetics Consortium,
Valdes AM
Studies:
Type 1 Diabetes Genetics Consortium
Several studies have indicated that genes in the human leucocyte antigen (HLA) region additional to the HLA class II DRB1-DQB1 contribute to type 1 diabetes (T1D) susceptibility. The aim of this study was to assess if markers in the class III Major Histocompatibility Complex (MHC) region are associated with T1D after accounting for linkage disequilibrium (LD) with DRB1-DQB1.