PubMed ID:
18840781
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
DOI:
https://doi.org/10.2337/db08-1022
Authors:
Annaiah K,
Bradfield JP,
Chiavacci RM,
DCCT/EDIC Research Group,
Eckert AW,
Frackelton EC,
Glessner JT,
Grabs R,
Grant SF,
Grundmeier RW,
Hakonarson H,
Imielinski M,
Kim CE,
Kirsch SE,
Lawson ML,
Marchand L,
Monos DS,
Otieno FG,
Paterson AD,
Polychronakos C,
Qu HQ,
Santa E,
Shaner JL,
Skraban R,
Smith RM,
Stanley CA,
Taback SP,
Waggott D
Studies:
Diabetes Control and Complications Trial
Two recent genome-wide association (GWA) studies have revealed novel loci for type 1 diabetes, a common multifactorial disease with a strong genetic component. To fully utilize the GWA data that we had obtained by genotyping 563 type 1 diabetes probands and 1,146 control subjects, as well as 483 case subject-parent trios, using the Illumina HumanHap550 BeadChip, we designed a full stage 2 study to capture other possible association signals.