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PubMed ID:
18353390
Public Release Type:
Journal
Publication Year: 2008
Affiliation: Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
DOI:
https://doi.org/10.1016/j.juro.2008.01.028
Authors:
Schaeffer AJ,
Koch AE,
Landis JR,
Pope RM,
Thumbikat P,
Shahrara S,
Sobkoviak R,
Stern JA,
Campbell PL,
Desireddi NV,
Chuai S
Studies:
Chronic Prostatitis Collaborative Research Network
The chronic pelvic pain syndrome is characterized by pelvic pain, voiding symptoms and varying degrees of inflammation within expressed prostatic secretions. We evaluated the chemokines monocyte chemoattractant protein 1 (CCL2) and macrophage inflammatory protein-1alpha (CCL3) in expressed prostatic secretions to identify marker increases associated with inflammatory (IIIA) and noninflammatory (IIIB) chronic pelvic pain syndrome. In addition, chemokine levels were correlated with clinical pain as determined by the National Institutes of Health chronic prostatitis symptom index.
