PubMed ID:
14763914
Public Release Type:
Journal
Publication Year: 2004
Affiliation: Hormones and Cancer Group, International Agency for Research on Cancer, Lyon, France. lukanova@iarc.fr
DOI:
https://doi.org/10.1530/eje.0.1500161
Authors:
Arslan A,
Berrino F,
Dossus L,
Hallmans G,
Kaaks R,
Koenig KL,
Krogh V,
Lenner P,
Lukanova A,
Lundin E,
Micheli A,
Mure A,
Muti P,
Riboli E,
Rinaldi S,
Shore RE,
Stattin P,
Toniolo P,
Zeleniuch-Jacquotte A
Studies:
Longitudinal Assessment of Bariatric Surgery
Excess weight has been associated with increased risk of cancer at several organ sites. In part, this effect may be modulated through alterations in the metabolism of sex steroids and IGF-I related peptides. The objectives of the study were to examine the association of body mass index (BMI) with circulating androgens (testosterone, androstenedione and dehydroepiandrosterone sulfate (DHEAS)), estrogens (estrone and estradiol), sex hormone-binding globulin (SHBG), IGF-I and IGF-binding protein (IGFBP)-3, and the relationship between sex steroids, IGF-I and IGFBP-3.