PubMed ID:
10546023
Public Release Type:
Journal
Publication Year: 1999
Affiliation: Department of Medicine, University of Vermont, Burlington 05405, USA.
DOI:
https://doi.org/10.2337/diacare.22.11.1875
Authors:
Poehlman ET,
Tchernof A,
Toth MJ
Studies:
Longitudinal Assessment of Bariatric Surgery
Low sex hormone-binding globulin (SHBG) levels in women are associated not only with hyperinsulinemia, increased risk for cardiovascular disease, and type 2 diabetes but also with excess body fatness and abdominal obesity. We tested the hypothesis that an elevated total or intra-abdominal adipose tissue accumulation mediates the relationship between low SHBG levels and an altered metabolic profile.