PubMed ID:
9580646
Public Release Type:
Journal
Publication Year: 1998
Affiliation: Department of Urology, Boston University Medical Center, MA 02118, USA.
DOI:
https://doi.org/10.1056/NEJM199805143382001
Authors:
Goldstein I,
Lue TF,
Padma-Nathan H,
Rosen RC,
Steers WD,
Wicker PA
Studies:
Longitudinal Assessment of Bariatric Surgery
Sildenafil is a potent inhibitor of cyclic guanosine monophosphate hydrolysis [corrected] in the corpus cavernosum and therefore increases the penile response to sexual stimulation. We evaluated the efficacy and safety of sildenafil, administered as needed in two sequential double-blind studies of men with erectile dysfunction of organic, psychogenic, and mixed causes.