PubMed ID:
8977760
Public Release Type:
Journal
Publication Year: 1996
Affiliation: Department of Endocrinology and Diabetes, General Hospital of Athens, Greece.
DOI:
https://doi.org/10.1046/j.1365-2265.1996.00795.x
Authors:
Chlouverakis CS,
Piaditis GP,
Rangou DB,
Spina J,
Stamataki KE
Studies:
Longitudinal Assessment of Bariatric Surgery
Although insulin has been shown to stimulate ovarian steroidogenesis and hyperinsulinaemia has been implicated in the raised androgen levels found in diseases associated with significant insulin resistance, ovarian function has not been studied so far in women with NIDDM. We have assessed ovarian function in women with NIDDM at the early (hyperinsulinaemic) and late (relative insulinopaenic) stages of evolution of the disease after strong stimulation with buserelin, a long-acting GnRH analogue. Significant differences in ovarian function would be expected, depending on the stage of evolution of NIDDM.