PubMed ID:
8580926
Public Release Type:
Journal
Publication Year: 1995
Affiliation: Department of Statistics, George Washington University, Rockville, Maryland 20852, USA.
DOI:
https://doi.org/10.1080/10543409508835111
Authors:
Bain RP,
Lachin JM,
Rosenberger WF
Studies:
Diabetes Control and Complications Trial
We present a nonparametric approach that tests whether multiple longitudinal measures tend in the same direction over time. It is not required that each measure have the same number of serial observations, or that the observations be evenly spaced. The test and related estimators of group differences are based on the multivariate rank test of Wei and Lachin (1) and multivariate Mann-Whitney shift estimators of Thall and Lachin (2) and Lachin (3). An example is given using a subset of exercise data from a clinical trial of vesnarinone in congestive heart failure.