PubMed ID:
2407096
Public Release Type:
Journal
Publication Year: 1990
Affiliation: University of Pennsylvania School of Medicine, Philadelphia.
DOI:
https://doi.org/10.1093/ajcn/51.2.167
Authors:
Crosby LO,
Feurer ID,
Foster GD,
Jennings AS,
Mullen JL,
Ship J,
Stunkard AJ,
Wadden TA
Studies:
Longitudinal Assessment of Bariatric Surgery
Resting energy expenditure (REE), weight, and body composition were measured up to seven times in 13 obese women during a 24-wk study. Patients were randomly assigned to a very-low-calorie diet (VLCD, 500 kcal/d) or a balanced-deficit diet (BDD, 1200 kcal/d). After 8 wk of supplemented fasting, REE of the VLCD patients decreased by 17% whereas that of the BDD patients was virtually unchanged. REE of the VLCD patients increased during 12 subsequent weeks of realimentation such that differences in REE between the two groups were not statistically significant at week 24 (VLCD = -11%, BDD = -2%). Reductions in weight and fat-free mass (FFM) were 12.1% and 3.6% for the VLCD patients and 10.6% and 4.1% for the BDD patients, respectively. There were no significant differences between the groups in pre- to posttreatment changes in REE normalized to FFM. Results suggest that REE recovers partially after consumption of a VLCD. They also provide evidence of a possible metabolic advantage of weight loss by a more moderate restriction.