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Publication Information
Affiliation
Renal Division, Brigham & Women's Hospital, Boston, MA.
Authors
Isakova T, Kaze AD, McMullan CJ, Srivastava A, Waikar SS
Studies
Citation
Srivastava A, Kaze AD, McMullan CJ, Isakova T, Waikar SS. Uric Acid and the Risks of Kidney Failure and Death in Individuals With CKD. Am J Kidney Dis 2018 Mar;71(3):362-370. Epub 2017 Nov 11.Abstract
Serum uric acid concentrations increase in chronic kidney disease (CKD) and may lead to tubular injury, endothelial dysfunction, oxidative stress, and intrarenal inflammation. Whether uric acid concentrations are associated with kidney failure and death in CKD is unknown.