PubMed ID:
27569726
Public Release Type:
Journal
Publication Year: 2016
Affiliation: Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
DOI:
https://doi.org/10.1053/j.gastro.2016.08.027
Authors:
Hoofnagle JH,
Kleiner DE,
Kleiner DE,
Abrams SH,
Africa J,
Alazraki A,
Amsden K,
Angeles J,
Aouizerat B,
Arroyo S,
Awai H,
Baker SS,
Barlow S,
Barlow S,
Barlow SE,
Behling C,
Behr G,
Belt P,
Bernstein K,
Bozic M,
Bramlage K,
Bross C,
Brown S,
Brunt EM,
Brunt EM,
Cecil K,
Clark JM,
Clark JM,
Cleeton R,
Cooper K,
Courtier J,
Cruz Munos J,
Cummings OW,
Derdoy J,
DeVore S,
Donithan M,
Doo E,
Doo EC,
Durelle J,
Ferrell LD,
Fishbein MH,
Fleck S,
Fowler K,
Gill R,
Hallinan E,
Himes R,
Horslen S,
Hsu E,
Isaacson M,
Jain A,
Jain AK,
Kafka K,
Karpen S,
Karpen SJ,
King D,
Kirwan E,
Klipsch A,
Kohli R,
Kohli R,
Krisnamurthy R,
Lake K,
Langlois C,
Lavine JE,
Lavine JE,
Lefkowitch JH,
Mahabir R,
Maldonado L,
May KP,
Mencin A,
Middleton M,
Miriel L,
Mohammad S,
Molleston JP,
Molleston JP,
Munson S,
Murray K,
Murray KF,
NASH CRN,
Neuschwander-Tetri BA,
Newton K,
Osmack P,
Otto R,
Paiz M,
Perito ER,
Podberesky D,
Raviele N,
Reynoso E,
Rigsby C,
Robuck PR,
Rosenthal P,
Rosenthal P,
Sandrasegaran K,
Sanford J,
Scheimann A,
Schwimmer JB,
Schwimmer JB,
Sharda L,
Sherker A,
Siegner J,
Sirlin C,
Sternberg A,
Stewart S,
Subbarao G,
Tonascia J,
Tonascia J,
Torrance R,
Torretta S,
Towbin A,
Tsai P,
Ugalde-Nicalo P,
Van Natta M,
Van Natta ML,
Vaughn I,
Villarreal MD,
Vos M,
Vos MB,
Whitington PF,
Whitington PF,
Wilson L,
Wilson LA,
Wriston K,
Xanthakos S,
Xanthakos SA,
Yates K,
Yeh M,
Young M,
Zhu L
Studies:
Cysteamine Bitartrate Delayed-Release for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in Children
No treatment for nonalcoholic fatty liver disease (NAFLD) has been approved by regulatory agencies. We performed a randomized controlled trial to determine whether 52 weeks of cysteamine bitartrate delayed release (CBDR) reduces the severity of liver disease in children with NAFLD.