NIDDK Central Repository - Strategy and rationale for urine collection protocols employed in the NEPTUNE study.

An official website of the United States government

NIDDK Central Repository

Publication Information

DOI

10.1186/s12882-015-0185-3

PubMed ID

26577187

Public Release Type

Journal

Publication Year

2015

Affiliation

Department of Internal Medicine - Nephrology, University of Michigan Health System, Ann Arbor, MI, USA. markusbi@umich.edu.

Authors

Adler SG, Bitzer M, Harris PC, Heyer CM, Hogan MC, Holzmann LB, Ju W, Kopp JB, Kretzler M, Lienczewski CC, Lieske JC, Manganelli L, Nelson PJ, Nesbitt LL, Reich HN, Sundsbak JL, Ward CJ, Wickman LT

Studies

NEPTUNE

Citation

Hogan MC, Lieske JC, Lienczewski CC, Nesbitt LL, Wickman LT, Heyer CM, Harris PC, Ward CJ, Sundsbak JL, Manganelli L, Ju W, Kopp JB, Nelson PJ, Adler SG, Reich HN, Holzmann LB, Kretzler M, Bitzer M. Strategy and rationale for urine collection protocols employed in the NEPTUNE study. BMC Nephrol 2015 Nov 17;16:190.

Abstract

Glomerular diseases are potentially fatal, requiring aggressive interventions and close monitoring. Urine is a readily-accessible body fluid enriched in molecular signatures from the kidney and therefore particularly suited for routine clinical analysis as well as development of non-invasive biomarkers for glomerular diseases.