NIDDK Central Repository - Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes Study.

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NIDDK Central Repository

Publication Information

DOI

10.1016/S2213-8587(15)00291-0

PubMed ID

26377054

Public Release Type

Journal

Publication Year

2015

Authors

Diabetes Prevention Program Research Group

Studies

DPPOS

Citation

Diabetes Prevention Program Research Group. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes Study. Lancet Diabetes Endocrinol 2015 Nov;3(11):866-75. Epub 2015 Sep 13.

Abstract

Effective prevention is needed to combat the worldwide epidemic of type 2 diabetes. We investigated the long-term extent of beneficial effects of lifestyle intervention and metformin on diabetes prevention, originally shown during the 3-year Diabetes Prevention Program (DPP), and assessed whether these interventions reduced diabetes-associated microvascular complications.