PubMed ID:
25651489
Public Release Type:
Journal
Publication Year: 2015
Affiliation: *Pediatrics and Biochemistry, Saint Louis University, Cardinal Glennon Children's Medical Center, St Louis, MO †Pediatrics and Surgery, University of California San Francisco, San Francisco ‡Biostatistics, University of Michigan, Ann Arbor, MI §Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL ||Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles, Los Angeles, CA ¶Pediatric Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA #Pediatrics, Washington University, St Louis, MO **Pediatrics, Mount Sinai School of Medicine, New York, NY ††Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston ‡‡Pediatric Gastroenterology and Hepatology, Children's Hospital Medical Center, Cincinnati, OH §§Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, Canada ||||Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD ¶¶Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA ##Surgery, University of Michigan School of Medicine, Ann Arbor ***Pediatric Gastroenterology, Hepatology and Nutrition, James Whitcomb Riley Hospital for Children, Indianapolis, IN †††Pediatrics, Emory University, Children's Healthcare Atlanta, Atlanta, GA ‡‡‡Pediatrics, University of Pittsburgh, Pittsburgh, PA §§§National Institute of Diabetes, Digestive and Kidney Disease, National Institutes of Health, Baltimore, MD ||||||Pediatric Gastroenterology, University of Colorado, Children's Hospital Colorado, Aurora.
DOI:
https://doi.org/10.1097/MPG.0000000000000753
Authors:
Teckman JH,
Childhood Liver Disease Research Network (ChiLDReN),
Sokol RJ,
Sherker AH,
Shneider BL,
Romero R,
Molleston JP,
Magee JC,
Loomes KM,
Karnsakul W,
Kamath BM,
Hertel PM,
Heubi J,
Arnon R,
Spino C,
Thomas DW,
Rudnick DA,
Murray KF,
Michail S,
Bass LM,
Abel R,
Rosenthal P
Studies:
A Prospective Database of Infants With Cholestasis
,
ChiLDReN Network
,
Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis
α-1-Antitrypsin (A1AT) deficiency is a common genetic disease with an unpredictable and highly variable course. The Childhood Liver Disease Research and Education Network is a National Institutes of Health, multicenter, longitudinal consortium studying pediatric liver diseases, with the objective of prospectively defining natural history and identifying disease modifiers.