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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2015
Affiliation
*Pediatrics and Biochemistry, Saint Louis University, Cardinal Glennon Children's Medical Center, St Louis, MO †Pediatrics and Surgery, University of California San Francisco, San Francisco ‡Biostatistics, University of Michigan, Ann Arbor, MI §Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL ||Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles, Los Angeles, CA ¶Pediatric Gastroenterology and Hepatology, Seattle Children's Hospital, Seattle, WA #Pediatrics, Washington University, St Louis, MO **Pediatrics, Mount Sinai School of Medicine, New York, NY ††Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston ‡‡Pediatric Gastroenterology and Hepatology, Children's Hospital Medical Center, Cincinnati, OH §§Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, Canada ||||Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD ¶¶Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA ##Surgery, University of Michigan School of Medicine, Ann Arbor ***Pediatric Gastroenterology, Hepatology and Nutrition, James Whitcomb Riley Hospital for Children, Indianapolis, IN †††Pediatrics, Emory University, Children's Healthcare Atlanta, Atlanta, GA ‡‡‡Pediatrics, University of Pittsburgh, Pittsburgh, PA §§§National Institute of Diabetes, Digestive and Kidney Disease, National Institutes of Health, Baltimore, MD ||||||Pediatric Gastroenterology, University of Colorado, Children's Hospital Colorado, Aurora.
Authors
Abel R, Arnon R, Bass LM, Childhood Liver Disease Research Network (ChiLDReN), Hertel PM, Heubi J, Kamath BM, Karnsakul W, Loomes KM, Magee JC, Michail S, Molleston JP, Murray KF, Romero R, Rosenthal P, Rudnick DA, Sherker AH, Shneider BL, Sokol RJ, Spino C, Teckman JH, Thomas DW
Studies
Citation
Teckman JH, Rosenthal P, Abel R, Bass LM, Michail S, Murray KF, Rudnick DA, Thomas DW, Spino C, Arnon R, Hertel PM, Heubi J, Kamath BM, Karnsakul W, Loomes KM, Magee JC, Molleston JP, Romero R, Shneider BL, Sherker AH, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Baseline Analysis of a Young α-1-Antitrypsin Deficiency Liver Disease Cohort Reveals Frequent Portal Hypertension. J Pediatr Gastroenterol Nutr 2015 Jul;61(1):94-101.

Abstract

α-1-Antitrypsin (A1AT) deficiency is a common genetic disease with an unpredictable and highly variable course. The Childhood Liver Disease Research and Education Network is a National Institutes of Health, multicenter, longitudinal consortium studying pediatric liver diseases, with the objective of prospectively defining natural history and identifying disease modifiers.