PubMed ID:
25863217
Public Release Type:
Journal
Publication Year: 2015
Affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand; Department of Surgery, University of Auckland, Auckland, New Zealand. Electronic address: greg.ogrady@auckland.ac.nz.
DOI:
https://doi.org/10.1053/j.gastro.2015.04.003
Authors:
Abell TL,
Angeli TR,
Bernard CE,
Cheng LK,
Du P,
Farrugia G,
Faussone-Pellegrini MS,
Lahr C,
O'Grady G,
Vannucchi MG,
Vather R,
Wang TH,
Windsor JA
Studies:
Gastroparesis Clinical Research Consortium
,
Nortriptyline for Idiopathic Gastroparesis
Chronic unexplained nausea and vomiting (CUNV) is a debilitating disease of unknown cause. Symptoms of CUNV substantially overlap with those of gastroparesis, therefore the diseases may share pathophysiologic features. We investigated this hypothesis by quantifying densities of interstitial cells of Cajal (ICCs) and mapping slow-wave abnormalities in patients with CUNV vs controls.