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Publication Information
Affiliation
Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand; Department of Surgery, University of Auckland, Auckland, New Zealand. Electronic address: greg.ogrady@auckland.ac.nz.
Authors
Abell TL, Angeli TR, Bernard CE, Cheng LK, Du P, Farrugia G, Faussone-Pellegrini MS, Lahr C, O'Grady G, Vannucchi MG, Vather R, Wang TH, Windsor JA
Studies
Citation
Angeli TR, Cheng LK, Du P, Wang TH, Bernard CE, Vannucchi MG, Faussone-Pellegrini MS, Lahr C, Vather R, Windsor JA, Farrugia G, Abell TL, O'Grady G. Loss of Interstitial Cells of Cajal and Patterns of Gastric Dysrhythmia in Patients With Chronic Unexplained Nausea and Vomiting. Gastroenterology 2015 Jul;149(1):56-66.e5. Epub 2015 Apr 8.Abstract
Chronic unexplained nausea and vomiting (CUNV) is a debilitating disease of unknown cause. Symptoms of CUNV substantially overlap with those of gastroparesis, therefore the diseases may share pathophysiologic features. We investigated this hypothesis by quantifying densities of interstitial cells of Cajal (ICCs) and mapping slow-wave abnormalities in patients with CUNV vs controls.