PubMed ID:
25066359
Public Release Type:
Journal
Publication Year: 2014
Affiliation: Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA; Salt Lake City VA Health Care System, Salt Lake City, UT, USA.
DOI:
https://doi.org/10.1111/nep.12315
Authors:
Greene T,
Raphael KL,
Ying J,
Zhang Y
Request IDs:
6228
Studies:
Chronic Renal Insufficiency Cohort Study
The prevalence of metabolic acidosis increases as glomerular filtration rate falls. However, most patients with stage 4 chronic kidney disease have normal serum bicarbonate concentration while some with stage 3 chronic kidney disease have low serum bicarbonate, suggesting that other factors contribute to generation of acidosis. The purpose of this study is to identify risk factors, other than reduced glomerular filtration rate, for reduced serum bicarbonate in chronic kidney disease.