NIDDK Central Repository - Estimated albumin excretion rate versus urine albumin-creatinine ratio for the estimation of measured albumin excretion rate: derivation and validation of an estimated albumin excretion rate equation.

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NIDDK Central Repository

Publication Information

DOI

10.1053/j.ajkd.2013.08.009

PubMed ID

24084157

Public Release Type

Journal

Publication Year

2014

Affiliation

Sheffield Kidney Institute, Sheffield, United Kingdom; Department of Cardiovascular Science, University of Sheffield, Sheffield, United Kingdom. Electronic address: t.ellam@sheffield.ac.uk.

Authors

Campbell MJ, Ellam T, El Nahas M, Fogarty DG, Fotheringham J

Studies

MDRD, CRIC, DCCT

Citation

Fotheringham J, Campbell MJ, Fogarty DG, El Nahas M, Ellam T. Estimated albumin excretion rate versus urine albumin-creatinine ratio for the estimation of measured albumin excretion rate: derivation and validation of an estimated albumin excretion rate equation. Am J Kidney Dis 2014 Mar;63(3):405-14. Epub 2013 Sep 29.

Abstract

Glomerular filtration rate estimation equations use demographic variables to account for predicted differences in creatinine generation rate. In contrast, assessment of albuminuria from urine albumin-creatinine ratio (ACR) does not account for these demographic variables, potentially distorting albuminuria prevalence estimates and clinical decision making.