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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2013
Affiliation
Section of Hepatology, Division of Gastroenterology, Hepatology and Nutrition and the Hume-Lee Transplant Center, Virginia Commonwealth University, Richmond, VA, USA.
Authors
Acute Liver Failure Study Group, Bajaj JS, Cheng J, Lee WM, Mirshahi F, Reisch J, Sanyal AJ, Stravitz RT
Studies
Citation
Stravitz RT, Sanyal AJ, Reisch J, Bajaj JS, Mirshahi F, Cheng J, Lee WM, Acute Liver Failure Study Group. Effects of N-acetylcysteine on cytokines in non-acetaminophen acute liver failure: potential mechanism of improvement in transplant-free survival. Liver Int 2013 Oct;33(9):1324-31. Epub 2013 Jun 19.

Abstract

N-Acetylcysteine (NAC) improves transplant-free survival in patients with non-acetaminophen acute liver failure (ALF) when administered in early stages of hepatic encephalopathy. The mechanisms of this benefit are unknown.