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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2013
Affiliation
Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden. harvest.gu@ki.se
Authors
Abu Seman N, Botusan IR, Brismar K, Catrina SB, Gu HF, Gu T, Lokman EF, Sunkari VG, Zheng X
Studies
Citation
Gu HF, Zheng X, Abu Seman N, Gu T, Botusan IR, Sunkari VG, Lokman EF, Brismar K, Catrina SB. Impact of the hypoxia-inducible factor-1 α (HIF1A) Pro582Ser polymorphism on diabetes nephropathy. Diabetes Care 2013 Feb;36(2):415-21. Epub 2012 Sep 18.

Abstract

Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN.