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PubMed ID:
22643349
Public Release Type:
Journal
Publication Year: 2012
Affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand; Department of Surgery, Vanderbilt University, Nashville, Tennessee.
DOI:
https://doi.org/10.1053/j.gastro.2012.05.036
Authors:
Angeli TR,
O'Grady G,
Cheng LK,
Pullan AJ,
Farrugia G,
Abell TL,
Windsor JA,
Lammers WJEP,
Lahr C,
Du P
Studies:
Gastroparesis Clinical Research Consortium
,
Nortriptyline for Idiopathic Gastroparesis
Interstitial cells of Cajal (ICC) generate slow waves. Disrupted ICC networks and gastric dysrhythmias are each associated with gastroparesis. However, there are no data on the initiation and propagation of slow waves in gastroparesis because research tools have lacked spatial resolution. We applied high-resolution electrical mapping to quantify and classify gastroparesis slow-wave abnormalities in spatiotemporal detail.
