PubMed ID:
22153382
Public Release Type:
Journal
Publication Year: 2012
Affiliation: Nutrition and Neurocognition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA. troen@agri.huji.ac.il
DOI:
https://doi.org/10.1053/j.jrn.2011.07.009
Authors:
Alfrey EJ,
Anandagoda Lde S,
Anderson-Haag T,
Armbruster B,
Berndt M,
Blackmore J,
Bolin P Jr,
Bolognani S,
Bostom A,
Bresnahan B,
Bryant W,
Bullas R,
Carpenter MA,
Clark R,
Coffman J,
Cole E,
Cosio F,
Dallal GE,
D'Anci KE,
Diltz C,
Dobson B,
Edgar MJ,
Edwards C,
FACT Study Investigators,
Famure S,
Farag YM,
Ford H,
Garris C,
Garrison K,
Gaynor S,
Gifford-Hollingsworth C,
Giordan M,
Gnadt C,
Groth J,
Hertello P,
House A,
Hunsicker L,
Jacques PF,
Jones P,
Kasiske B,
Kendrach A,
Kew CE 2nd,
Kumar A,
LaBeck T,
Levey AS,
Lion M,
Lowe T,
Lyman PR,
Mace N,
Mahler K,
McDaniel B,
McDaniel B,
McKenney J,
McRae E,
Medeiros M,
Miedwig L,
Moorthy D,
Norman D,
Okano I,
Osborne J,
Pacheco-Silva A,
Pagels J,
Parker K,
Parks R,
Pence D,
Pesavento T,
Pirsch J,
Quintino P,
Radke N,
Riley J,
Rogers G,
Rosenberg IH,
Sanmugalingham G,
Scott TM,
Selhub J,
Seliger S,
Singh A,
Smith SR,
Sundberg AK,
Troen AM,
Vella J,
Vermillion M,
Wallace W,
Weiner DE,
Weir M,
Young C
Studies:
Folic Acid for Vascular Outcome Reduction in Transplantation Trial
Hyperhomocysteinemia and B-vitamin deficiency may be treatable risk factors for cognitive impairment and decline. Hyperhomocysteinemia, cognitive impairment, and depression are all common in individuals with kidney disease, including kidney transplant recipients. Accordingly, we assessed the prevalence of cognitive impairment and depressive symptoms in transplant recipients and their association with kidney function, plasma total homocysteine, and B-vitamin concentrations.