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PubMed ID:
37781457
Public Release Type:
Journal
Publication Year: 2023
Affiliation: 1Minami Diabetes Clinical Research Center, Fukuoka, Japan, 2Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 3Clinic Masae Minami, Fukuoka, Japan, 4Shiraya Eye Clinic, Tokyo, Japan, 5Adachi Medical Center, Tokyo Women's Medical University, Tokyo, Japan?
DOI:
https://doi.org/10.1007/s13340-023-00654-w
Authors:
Hirose A,
Maeda Y,
Goto A,
Minami M,
Kitano S,
Uchigata Y
Request IDs:
22716
Studies:
Diabetes Control and Complications Trial / Epidemiology of Diabetes Interventions and Complications
OBJECTIVE: To examine if there was a variable of glycemic exposure having a common linear relation against retinopathy level regardless of duration of diabetes which might contribute to diabetes care through retinopathy prediction, we analyzed data from the Diabetes Control and Complications Trial/ Epidemiology of Diabetes Interventions and Complications. RESEARCH DESIGN AND METHODS: To exclude possible disturbing effect of metabolic memory, we examined only selected subgroup of participants who had glycohemoglobin A1c (A1C) data of total period of type 1 diabetes. Relations between three A1C variables and retinopathy at three different timepoints of duration were compared using simple linear regression analysis. RESULTS: Between only ?excessA1C and retinopathy, the linear regression lines at the three timepoints appeared to be similar in both slope and intercept. CONCLUSIONS: ?excessA1C, the sum of yearly excess A1C during total period of diabetes, may have a potential to predict retinopathy regardless of duration in type1 diabetes.
