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Publication Information
Affiliation
Authors
Afdhal NH, Belle SH, Doo EC, Fried MW, Hawke RL, Meyers CM, Navarro VJ, Reddy KR, The SYNCH Study Group, Wahed AS
Studies
Citation
Fried MW, Navarro VJ, Afdhal NH, Belle SH, Wahed AS, Hawke RL, Doo EC, Meyers CM, Reddy KR, The SYNCH Study Group. A Randomized, Placebo-Controlled Trial of Oral Silymarin (Milk Thistle) For Chronic Hepatitis C: Final Results of the SYNCH Multicenter Study. Hepatology 2011 Oct;54(Suppl S1):475A.Abstract
The botanical extract silymarin, commonly known
as milk thistle, is a polyphenolic flavonoid with anti-oxidant,
anti-inflammatory, and immunomodulatory properties in vitro
and is used extensively by patients with chronic liver disease.
This trial evaluated the effect of high doses of oral silymarin on
disease activity in patients with chronic hepatitis C.