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PubMed ID:
21843518
Public Release Type:
Journal
Publication Year: 2011
Affiliation: Department of Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada. JL.Mahon@lhsc.on.ca
DOI:
https://doi.org/10.1016/j.cca.2011.07.019
Authors:
Skyler JS,
Palmer JP,
Boulware DC,
Marcovina SM,
Beam CA,
Mahon JL,
Type 1 Diabetes TrialNet Study Group,
Krischer JP,
Winter WE
Studies:
Diabetes Prevention Trial of Type 1 Diabetes
Detection of below-threshold first-phase insulin release or FPIR (1+3 minute insulin concentrations during an intravenous glucose tolerance test [IVGTT]) is important in type 1 diabetes prediction and prevention studies including the TrialNet Oral Insulin Prevention Trial. We assessed whether an insulin immunoenzymometric assay (IEMA) could replace the less practical but current standard of a radioimmunoassay (RIA) for FPIR.
