NIDDK Central Repository - Transmission distortion in Crohn's disease risk gene ATG16L1 leads to sex difference in disease association.

An official website of the United States government

NIDDK Central Repository

Publication Information

DOI

10.1002/ibd.21781

PubMed ID

21618365

Public Release Type

Journal

Publication Year

2012

Affiliation

Stanford Center for Biomedical Informatics Research, Stanford University School of Medicine, Stanford, California 94305-5415, USA.

Authors

Butte AJ, Liu LY, Schaub MA, Sirota M

Studies

IBD

Citation

Liu LY, Schaub MA, Sirota M, Butte AJ. Transmission distortion in Crohn's disease risk gene ATG16L1 leads to sex difference in disease association. Inflamm Bowel Dis 2012 Feb;18(2):312-22. Epub 2011 May 25.

Abstract

Crohn's disease (CD), an inflammatory disease of the bowel, affects millions of people around the world. Evidence suggests that disease onset and pathogenesis differ between males and females. Yet no comprehensive efforts exist to assess the sex-specific genetic architecture of CD.