NIDDK Central Repository - Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography.

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NIDDK Central Repository

Publication Information

DOI

10.1016/j.jhep.2011.04.020

PubMed ID

21703173

Public Release Type

Journal

Publication Year

2012

Affiliation

Section of Hepatology and Hume-Lee Transplant Center, Virginia Commonwealth University, Richmond, VA 23298-0341, USA. rstravit@vcu.edu

Authors

Fuchs M, Ibrahim A, Lee WM, Lisman T, Luketic VA, Puri P, Sanyal AJ, Sterling RK, Stravitz RT

Studies

AALF

Citation

Stravitz RT, Lisman T, Luketic VA, Sterling RK, Puri P, Fuchs M, Ibrahim A, Lee WM, Sanyal AJ. Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography. J Hepatol 2012 Jan;56(1):129-36. Epub 2011 May 19.

Abstract

Patients with acute liver injury/failure (ALI/ALF) are assumed to have a bleeding diathesis on the basis of elevated INR; however, clinically significant bleeding is rare. We hypothesized that patients with ALI/ALF have normal hemostasis despite elevated INR.