PubMed ID:
21703173
Public Release Type:
Journal
Publication Year: 2012
Affiliation: Section of Hepatology and Hume-Lee Transplant Center, Virginia Commonwealth University, Richmond, VA 23298-0341, USA. rstravit@vcu.edu
DOI:
https://doi.org/10.1016/j.jhep.2011.04.020
Authors:
Lisman T,
Lee WM,
Stravitz RT,
Sterling RK,
Fuchs M,
Ibrahim A,
Luketic VA,
Puri P,
Sanyal AJ
Studies:
Acute Liver Failure Study Group: Adult Acute Liver Failure Study
Patients with acute liver injury/failure (ALI/ALF) are assumed to have a bleeding diathesis on the basis of elevated INR; however, clinically significant bleeding is rare. We hypothesized that patients with ALI/ALF have normal hemostasis despite elevated INR.