PubMed ID:
21325864
Public Release Type:
Journal
Publication Year: 2011
Affiliation: Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Deutschland.
DOI:
https://doi.org/10.1159/000323768
Authors:
König IR,
Loley C,
Ziegler A
Studies:
Inflammatory Bowel Disease Genetics
Genome-wide association studies have successfully elucidated the genetic background of complex diseases, but X chromosomal data have usually not been analyzed. A reason for this is that there is no consensus approach for the analysis taking into account the specific features of X chromosomal data. This contribution evaluates test statistics proposed for X chromosomal markers regarding type I error frequencies and power.