PubMed ID:
20464532
Public Release Type:
Journal
Publication Year: 2010
Affiliation: Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. rpbusui@umich.edu
DOI:
https://doi.org/10.1007/s11892-010-0120-8
Authors:
Herman WH,
Albers JW,
Cleary PA,
DCCT/EDIC Research Group,
Feldman EL,
Lachin JM,
Low PA,
Martin CL,
Pop-Busui R,
Waberski BH
Studies:
Diabetes Control and Complications Trial
The DCCT/EDIC (Diabetes Control and Complications Trial/ Epidemiology of Diabetes Interventions and Complications) provides a comprehensive characterization of the natural history of diabetic neuropathy in patients with type 1 diabetes and provides insight into the impact of intensive insulin therapy in disease progression. The lessons learned about the natural history of distal symmetrical polyneuropathy and cardiovascular autonomic neuropathy and the impact of glycemic control on neuropathy are discussed in this review.