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Publication Information
Affiliation
University of Texas Southwestern Medical Center at Dallas, TX, USA. beg81@mac.com <beg81@mac.com>
Authors
Acute Liver Failure Study Group, Gregory B, Larson AM, Lee WM, Reisch J
Studies
Citation
Gregory B, Larson AM, Reisch J, Lee WM, Acute Liver Failure Study Group. Acetaminophen dose does not predict outcome in acetaminophen-induced acute liver failure. J Investig Med 2010 Jun;58(5):707-10.Abstract
Acetaminophen is a dose-dependent toxin. Prognosis in severe acute liver injury is related presumably in part to the dose ingested. We sought to assess the value of acetaminophen dosing information in patients with acute liver failure (ALF) due to acetaminophen toxicity to determine the role of dose as a prognostic indicator.