PubMed ID:
20305573
Public Release Type:
Journal
Publication Year: 2010
Affiliation: University of Texas Southwestern Medical Center at Dallas, TX, USA. beg81@mac.com <beg81@mac.com>
DOI:
https://doi.org/10.231/JIM.0b013e3181db8764
Authors:
Acute Liver Failure Study Group,
Reisch J,
Lee WM,
Gregory B,
Larson AM
Studies:
Acute Liver Failure Study Group: Adult Acute Liver Failure Study
Acetaminophen is a dose-dependent toxin. Prognosis in severe acute liver injury is related presumably in part to the dose ingested. We sought to assess the value of acetaminophen dosing information in patients with acute liver failure (ALF) due to acetaminophen toxicity to determine the role of dose as a prognostic indicator.