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Publication Information
Affiliation
Department of Medicine, University of Pisa School of Medicine, Pisa, Italy. ferranni@ifc.cnr.it
Authors
DPT-1 Study Group, Ferrannini E, Mari A, Nofrate V, Skyler JS, Sosenko JM
Studies
Citation
Ferrannini E, Mari A, Nofrate V, Sosenko JM, Skyler JS, DPT-1 Study Group. Progression to diabetes in relatives of type 1 diabetic patients: mechanisms and mode of onset. Diabetes 2010 Mar;59(3):679-85. Epub 2009 Dec 22.Abstract
Relatives of type 1 diabetic patients are at enhanced risk of developing diabetes. We investigated the mode of onset of hyperglycemia and how insulin sensitivity and beta-cell function contribute to the progression to the disease.