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PubMed ID:
19878986
Public Release Type:
Journal
Publication Year: 2009
DOI:
https://doi.org/10.1016/S0140-6736(09)61457-4
Authors:
Weinzierl V,
Williams-Cleaves B,
Metzger BE,
Molitch ME,
Johnson MK,
Giles MM,
Larsen D,
Niznik C,
Pen SC,
Schinleber PA,
Nathan DM,
McKitrick C,
Turgeon H,
Abbott K,
Altshuler D,
Anderson E,
Bissett L,
Cagliero E,
D'Anna K,
Delahanty L,
Florez JC,
Goldman V,
Poulos A,
Tseng B,
Barrett-Connor E,
Carrion-Petersen ML,
Horne J,
Leos D,
Mudaliar S,
Smith J,
Vejvoda K,
Pi-Sunyer FX,
Lee JE,
Foo ST,
Hagamen S,
Marrero DG,
Kelly SM,
Ackermann RT,
Fineberg ES,
Hadden A,
Jackson MA,
Kirkman MS,
Mather KJ,
Roach PJ,
Wheeler ML,
Ratner RE,
Aroda V,
Shapiro S,
Bavido-Arrage C,
Gibbs P,
Uwaifo G,
Wiggins R,
Saad MF,
Watson K,
Botrous M,
Jinagouda S,
Budget M,
Conzues C,
Magpuri P,
Ngo K,
Xapthalamous K,
White NH,
Das S,
Santiago A,
Brown AL,
Wernimont C,
Saudek CD,
Whittington T,
Clark JM,
Greene A,
Jiggetts D,
Mosley H,
Reusing J,
Rubin RR,
Stephen S,
Utsey E,
Schade DS,
Adams KS,
Hemphill C,
Hyde P,
Butler L,
Canady JL,
Colleran K,
Gonzales Y,
Hernandez-McGinnis DA,
Katz P,
King C,
Crandall J,
Brown-Friday JO,
Adorno E,
Duffy H,
Martinez H,
Pompi D,
Shamoon H,
Walker EA,
Wylie-Rosett J,
Orchard T,
Jeffries S,
Kramer MK,
Smith M,
Kriska A,
Pettigrew J,
Semler L,
Venditti E,
Arakaki RF,
Baker-Ladao NK,
Isonaga MK,
Bermudez NE,
Mau MK,
Knowler WC,
Cooeyate N,
Hoskin MA,
Natewa C,
Percy CA,
Acton KJ,
Andre VL,
Begay S,
Bucca BC,
Cook S,
Doughty MS,
Glass J,
Glass M,
Hanson RL,
Hassenpflug D,
Ingraham LE,
Kobus KM,
Krakoff J,
Manus C,
McCabe C,
Michaels S,
Morgan T,
Nelson JA,
Roy RJ,
Smart M,
Tonemah DP,
Wilson C,
Fowler S,
Brenneman T,
Abebe S,
Bamdad J,
Callaghan J,
Christophi CA,
Edelstein SL,
Gao Y,
Gooding R,
Gottlieb A,
Grover N,
Hoffman H,
Jablonski K,
Katz R,
Kolinjivadi P,
Lachin JM,
Ma Y,
Reamer S,
Sapozhnikova A,
Sherif H,
Temprosa M,
Venditti EM,
Kriska AM,
Semler L,
Weinzierl V,
Marcovina S,
Strylewicz G,
Albers J,
Prineas RJ,
Alexander T,
Campbell C,
Hall S,
Hensley S,
Li Y,
Mills M,
Soliman E,
Zhang Z,
Fradkin J,
Garfield S,
Mayer-Davis E,
Moran RR,
Ganiats T,
Sarkin AJ,
Diabetes Prevention Program Research Group,
Knowler WC,
Fowler SE,
Hamman RF,
Christophi CA,
Hoffman HJ,
Brenneman AT,
Brown-Friday JO,
Goldberg R,
Venditti E,
Nathan DM,
Bray GA,
Chatellier A,
Duncan C,
Greenway FL,
Levy E,
Ryan DH,
Polonsky KS,
Tobian J,
Ehrmann D,
Matulik MJ,
Clark B,
Czech K,
DeSandre C,
Hilbrich R,
McNabb W,
Semenske AR,
Goldstein BJ,
Smith KA,
Wildman W,
Pepe C,
Goldberg RB,
Calles J,
Ojito J,
Castillo-Florez S,
Florez HJ,
Giannella A,
Lara O,
Veciana B,
Haffner SM,
Montez MG,
Lorenzo C,
Martinez A,
Hamman RF,
Testaverde L,
Bouffard A,
Dabelea D,
Jenkins T,
Lenz D,
Perreault L,
Price DW,
Steinke SC,
Horton ES,
Poirier CS,
Swift K,
Caballero E,
Jackson SD,
Lambert L,
Lawton KE,
Ledbury S,
Kahn SE,
Montgomery BK,
Fujimoto W,
Knopp RH,
Lipkin EW,
Marr M,
Murillo A,
Trence D,
Kitabchi AE,
Murphy ME,
Applegate WB,
Bryer-Ash M,
Dagogo-Jack S,
Frieson SL,
Lambeth H,
Lichtermann LC,
Otkaei H,
Rutledge LM,
Sherman AR,
Smith CM,
Soberman JE
Studies:
Diabetes Prevention Program Outcomes Study
In the 2.8 years of the Diabetes Prevention Program (DPP) randomised clinical trial, diabetes incidence in high-risk adults was reduced by 58% with intensive lifestyle intervention and by 31% with metformin, compared with placebo. We investigated the persistence of these effects in the long term.
