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Publication Information
Affiliation
Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Authors
Allison DB, Brock DW, Coffey CS, Desmond RA, Elobeid MA, Gadde KM, Heymsfield SB, Lu K, McVie T, Musser B, Padilla MA, St-Onge MP, Thomas O
Studies
Citation
Elobeid MA, Padilla MA, McVie T, Thomas O, Brock DW, Musser B, Lu K, Coffey CS, Desmond RA, St-Onge MP, Gadde KM, Heymsfield SB, Allison DB. Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods. PLoS One 2009 Aug 13;4(8):e6624.Abstract
Dropouts and missing data are nearly-ubiquitous in obesity randomized controlled trails, threatening validity and generalizability of conclusions. Herein, we meta-analytically evaluate the extent of missing data, the frequency with which various analytic methods are employed to accommodate dropouts, and the performance of multiple statistical methods.