NIDDK Central Repository - Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.

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NIDDK Central Repository

Publication Information

DOI

10.2337/db09-0641

PubMed ID

19651817

Public Release Type

Journal

Publication Year

2009

Affiliation

Research Division, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

Authors

Katavetin P, Krolewski AS, Kure M, Mychaleckyj JC, Pezzolesi MG, Poznik GD, Rich SS, Skupien J, Warram JH

Studies

GoKinD

Citation

Pezzolesi MG, Katavetin P, Kure M, Poznik GD, Skupien J, Mychaleckyj JC, Rich SS, Warram JH, Krolewski AS. Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy. Diabetes 2009 Nov;58(11):2698-702. Epub 2009 Aug 3.

Abstract

To examine the association between single nucleotide polymorphisms (SNPs) in the engulfment and cell motility 1 (ELMO1) gene, a locus previously shown to be associated with diabetic nephropathy in two ethnically distinct type 2 diabetic populations, and the risk of nephropathy in type 1 diabetes.