PubMed ID:
19247629
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Nephrology Research Group, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, Northern Ireland, UK. a.j.mcknight@qub.ac.uk
DOI:
https://doi.org/10.1007/s00125-009-1281-3
Authors:
Forsblom C,
Groop PH,
Maxwell AP,
McKnight AJ,
Parkkonen M,
Patterson CC,
Pettigrew KA,
Sadlier D,
Savage DA,
Warren 3/UK GoKinD Study Group,
Woodman AM
Studies:
The Genetics of Kidneys in Diabetes
SMAD proteins are involved in multiple signalling pathways and are key modulators of gene expression. We hypothesised that genetic variation in selected SMAD genes contributes to susceptibility to diabetic nephropathy.