PubMed ID:
19247629
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Nephrology Research Group, Queen's University of Belfast, c/o Regional Genetics Centre, Belfast City Hospital, Belfast, Northern Ireland, UK. a.j.mcknight@qub.ac.uk
DOI:
https://doi.org/10.1007/s00125-009-1281-3
Authors:
McKnight AJ,
Woodman AM,
Parkkonen M,
Patterson CC,
Savage DA,
Forsblom C,
Pettigrew KA,
Sadlier D,
Groop PH,
Maxwell AP,
Warren 3/UK GoKinD Study Group
Studies:
The Genetics of Kidneys in Diabetes
SMAD proteins are involved in multiple signalling pathways and are key modulators of gene expression. We hypothesised that genetic variation in selected SMAD genes contributes to susceptibility to diabetic nephropathy.