PubMed ID:
19193669
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Division of Gastroenterology and Hepatology, Department of Medicine, University of Colorado Denver, Colorado, USA.
DOI:
https://doi.org/10.1136/gut.2008.168948
Authors:
Castelblanco N,
Dillon SM,
Golden-Mason L,
Im KA,
Mengshol JA,
Rosen HR,
Virahep-C Study Group,
Wilson CC
Studies:
Viral Resistance to Antiviral Therapy of Chronic Hepatitis C
Dendritic cell (DC) defects may contribute to chronicity in hepatitis C virus (HCV) infection and determine response to PEG-interferon and ribavirin therapy via poor T cell stimulation. Studies to date have produced inconsistent results regarding DC maturation and function: no large study has examined DCs before and after therapy.