PubMed ID:
19143815
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Laboratory of Statistical Genetics, The Rockefeller University, New York, NY, USA. che@mail.rockefeller.edu
DOI:
https://doi.org/10.1111/j.1463-1326.2008.01003.x
Authors:
Li D,
Barral-Rodriguez S,
Diabetes Genetics Consortium,
Hamon S,
He C,
Ott J
Studies:
Type 1 Diabetes Genetics Consortium
The human Major Histocompatibility Complex (MHC) is a highly polymorphic genomic region occupying approximately 4 Mb on chromosome 6p21.3. The relationship between human MHC and type 1 diabetes (T1D) has been previously investigated. To fine map the disease locus in this region, we carried out both linkage and association analyses using the Type 1 Diabetes Genetics Consortium data.