NIDDK Central Repository - MHC fine mapping of human type 1 diabetes using the T1DGC data.

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NIDDK Central Repository

Publication Information

DOI

10.1111/j.1463-1326.2008.01003.x

PubMed ID

19143815

Public Release Type

Journal

Publication Year

2009

Affiliation

Laboratory of Statistical Genetics, The Rockefeller University, New York, NY, USA. che@mail.rockefeller.edu

Authors

Barral-Rodriguez S, Diabetes Genetics Consortium, Hamon S, He C, Li D, Ott J

Studies

T1DGC

Citation

He C, Hamon S, Li D, Barral-Rodriguez S, Ott J, Diabetes Genetics Consortium. MHC fine mapping of human type 1 diabetes using the T1DGC data. Diabetes Obes Metab 2009 Feb;11 Suppl 1:53-9.

Abstract

The human Major Histocompatibility Complex (MHC) is a highly polymorphic genomic region occupying approximately 4 Mb on chromosome 6p21.3. The relationship between human MHC and type 1 diabetes (T1D) has been previously investigated. To fine map the disease locus in this region, we carried out both linkage and association analyses using the Type 1 Diabetes Genetics Consortium data.