NIDDK Central Repository - Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype.

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NIDDK Central Repository

Publication Information

DOI

10.1111/j.1463-1326.2008.00998.x

PubMed ID

19143810

Public Release Type

Journal

Publication Year

2009

Affiliation

Wellcome Trust Sanger Institute, Cambridge, UK. rm2@sanger.ac.uk

Authors

Deloukas P, Hunt S, McGinnis R, McLaren W, Ranganath V, Type 1 Diabetes Genetics Consortium, Whittaker P

Studies

T1DGC

Citation

McGinnis R, McLaren W, Ranganath V, Whittaker P, Hunt S, Deloukas P, Type 1 Diabetes Genetics Consortium. Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype. Diabetes Obes Metab 2009 Feb;11 Suppl 1:8-16.

Abstract

The aim of this study was to test chromosomes carrying the same DRB1-DQA1-DQB1 haplotype for single nucleotide polymorphisms (SNPs) in the major histocompatibility complex (MHC) that might mark subgroups of the haplotype with different risks for type 1 diabetes (T1D).