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PubMed ID:
19052125
Public Release Type:
Journal
Publication Year: 2008
Affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University School of Medicine, 3635 Vista Ave., St. Louis, MO 63110, USA. dibiscam@slu.edu
DOI:
https://doi.org/10.1056/NEJMoa0707615
Authors:
Szabo G,
HALT-C Trial Investigators,
Dienstag JL,
Snow KK,
Morishima C,
Ghany MG,
Morgan TR,
Bonkovsky HL,
Lok AS,
Lee WM,
Wright EC,
Everhart JE,
Lindsay KL,
Everson GT,
Shiffman ML,
Di Bisceglie AM,
Greenson JK,
Fontana RJ,
Davis GL,
Goodman ZD,
Chen FY,
Tran D,
Padmanabhan L,
Naishadham D,
Mihova MS,
Massey LJ,
Curto TM,
Stoddard AM,
Hoefs JC,
Craig JR,
Sheik M,
Jamal MM,
Park C,
Rogers TE,
Malet PF,
Shelton J,
Crowder N,
Elbein R,
Govindarajan S,
Jones CB,
Bell MC,
Shankar R,
Chung M,
Gretch DR,
Hoofnagle JH,
Robuck PR,
Seeff LB,
Haynes-Williams V,
Rivera E,
Park Y,
Kleiner D,
Liang TJ,
Smith P,
Hofmann C,
Mills AS,
Contos MJ,
Milstein SL,
Perrillo RP,
Lemon SM,
Garcia-Tsao G,
Kutner M,
Sterling RK,
Richtmyer PA,
McKinley C,
DeSanto J,
Kugelmas M,
Nash SR,
Molchen WA,
Bhan AK,
Reid AE,
Chung RT,
King D,
Brunt EM,
Neuschwander-Tetri B,
Bacon B,
Kelley M,
Giansiracusa D,
Cormier M,
Banner BF
Studies:
The Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis Trial
In patients with chronic hepatitis C who do not have a response to antiviral treatment, the disease may progress to cirrhosis, liver failure, hepatocellular carcinoma, and death. Whether long-term antiviral therapy can prevent progressive liver disease in such patients remains uncertain.
