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Publication Information
Affiliation
Department of Biological Chemistry, School of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA.
Authors
Comer F, Hart GW, Hsieh-Wilson LC, Park K, Saudek CD, Wang Z
Studies
Citation
Wang Z, Park K, Comer F, Hsieh-Wilson LC, Saudek CD, Hart GW. Site-specific GlcNAcylation of human erythrocyte proteins: potential biomarker(s) for diabetes. Diabetes 2009 Feb;58(2):309-17. Epub 2008 Nov 4.Abstract
O-linked N-acetylglucosamine (O-GlcNAc) is upregulated in diabetic tissues and plays a role in insulin resistance and glucose toxicity. Here, we investigated the extent of GlcNAcylation on human erythrocyte proteins and compared site-specific GlcNAcylation on erythrocyte proteins from diabetic and normal individuals.