PubMed ID:
18984734
Public Release Type:
Journal
Publication Year: 2009
Affiliation: Department of Biological Chemistry, School of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA.
DOI:
https://doi.org/10.2337/db08-0994
Authors:
Wang Z,
Comer F,
Hart GW,
Hsieh-Wilson LC,
Park K,
Saudek CD
Studies:
Screening for Impaired Glucose Tolerance
O-linked N-acetylglucosamine (O-GlcNAc) is upregulated in diabetic tissues and plays a role in insulin resistance and glucose toxicity. Here, we investigated the extent of GlcNAcylation on human erythrocyte proteins and compared site-specific GlcNAcylation on erythrocyte proteins from diabetic and normal individuals.