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Publication Information
Affiliation
Women's Pelvic Medicine and Reconstructive Surgery, University of Alabama at Birmingham, 618 20th Street South, NHB 219, Birmingham, AL, 35233-7333, USA. hrichter@uabmc.edu
Authors
Abdo L, Ata R, Bragg C, Burgio K, Burgio KL, Butryn M, Carter K, Chang A, Coward P, Creasman J, Creasman JM, Dunlap J, Foster G, Franklin F, Gay L, Gilbert S, Gorin A, Grady D, Hahn ME, Hannum S, Hecht J, Hubbell A, Lepore-Ally A, Macer J, Marshall K, Monk T, Myers D, Myers DL, Niemeier H, Nillni Y, Pair L, Pierce P, Pinto A, Program to Reduce Incontinence by Diet and Exercise (PRIDE) Research Group, Quan J, Ranslow-Robles D, Richter H, Richter HE, Robinson N, Sepinwall D, Smith C, Subak L, Subak LL, Sung VW, Thompson S, Turman J, Vittinghoff E, West D, Wheeler TL, Wing R, Winn V, Wrenn A, Yang J, Zobel N
Studies
Citation
Richter HE, Creasman JM, Myers DL, Wheeler TL, Burgio KL, Subak LL, Program to Reduce Incontinence by Diet and Exercise (PRIDE) Research Group. Urodynamic characterization of obese women with urinary incontinence undergoing a weight loss program: the Program to Reduce Incontinence by Diet and Exercise (PRIDE) trial. Int Urogynecol J Pelvic Floor Dysfunct 2008 Dec;19(12):1653-8. Epub 2008 Aug 5.Abstract
The purpose of this study was to describe urodynamic characteristics of overweight or obese women with urinary incontinence and explore the relationship between urodynamic parameters, body mass index (BMI), and abdominal circumference (AC). One hundred ten women underwent a standardized cough stress test and urodynamic study. Eighty-six percent of women had urodynamic stress incontinence and 15% detrusor overactivity. Intra-abdominal pressure (Pabd) at maximum cystometric capacity (MCC) increased 0.4 cm H(2)O per kg/m(2) unit of BMI (95% confidence interval [CI] = 0.0,0.7, p = 0.04) and 0.4 cm H(2)O per 2 cm increase in AC (CI = 0.2, 0.7, p < 0.01). Intravesical pressure (Pves) at MCC increased 0.4 cm H(2)O per 2 cm increase in AC (CI = 0.0, 0.8, p = 0.05) but was not associated with BMI (p = 0.18). BMI and AC had a stronger association with Pabd than with Pves, suggesting a possible mechanism for the association between obesity and urinary incontinence.