PubMed ID:
18650371
Public Release Type:
Journal
Publication Year: 2008
Affiliation: Department of Clinical Biochemistry, Hull Royal Infirmary, Hull, UK. eric.kilpatrick@hey.nhs.uk
DOI:
https://doi.org/10.2337/dc08-0864
Authors:
Rigby AS,
Atkin SL,
Kilpatrick ES
Studies:
Diabetes Control and Complications Trial
Debate remains as to whether short- or long-term glycemic instability confers a risk of microvascular complications in addition to that predicted by mean glycemia alone. In this study, we analyzed data from the Diabetes Control and Complications Trial (DCCT) to assess the effect of A1C variability on the risk of retinopathy and nephropathy in patients with type 1 diabetes.